Publications

Lloyd Steele, Xiang Li Tan, Bayanne Olabi, Jing Mia Gao, Reiko Tanaka, Hywel C. Williams (2022). Determining the clinical applicability of machine learning models through assessment of reporting across skin phototypes and rarer skin cancer types: A systematic review. Journal of the European Academy of Dermatology & Venereology.

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Rahman Attar, Guillem Hurault, Zihao Wang, Ricardo Mokhtari, Kevin Pan, Bayanne Olabi, Eleanor Earp, Lloyd Steele, Hywel C. Williams, Reiko Tanaka (2022). Reliable detection of eczema areas for fully automated assessment of eczema severity from digital camera images.

Cite DOI MedRxiv

Guillem Hurault, Jean François Stalder, Sophie Mery, Alain Delarue, Markéta Saint Aroman, Gwendal Josse, Reiko Tanaka (2022). EczemaPred: A computational framework for personalised prediction of eczema severity dynamics. Clinical and Translational Allergy.

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Guillem Hurault, Kevin Pan, Ricardo Mokhtari, Bayanne Olabi, Eleanor Earp, Lloyd Steele, Hywel C. Williams, Reiko Tanaka (2022). Detecting eczema areas in digital images: an impossible task?. JID Innovations.

Cite Code DOI MedRxiv

Ariane Duverdier, Adnan Custovic, Reiko Tanaka (2022). Data-driven research on eczema: systematic characterization of the field and recommendations for the future. Clinical and Translational Allergy.

Cite Code DOI MedRxiv

Guillem Hurault, Evelien Roekevisch, Mandy .E. Schram, Krisztina Szegedi, Sanja Kezic, Maritza A. Middelkamp-Hup, Phyllis I. Spuls, Reiko Tanaka (2022). Can serum biomarkers predict the outcome of systemic immunosuppressive therapy in adult atopic dermatitis patients?. Skin and Health Disease.

Cite Code DOI MedRxiv

Takuya Miyano, Alan D. Irvine, Reiko Tanaka (2021). Model-based meta-analysis to optimise $\mathit{S.}$ $\mathit{aureus}$-targeted therapies for atopic dermatitis. JID Innovations.

Cite Code DOI MedRxiv

Guillem Hurault, Valentin Delorieux, Young‐Min Kim, Kangmo Ahn, Hywel C. Williams, Reiko Tanaka (2021). Impact of environmental factors in predicting daily severity scores of atopic dermatitis. Clinical and Translational Allergy.

Cite Code DOI MedRxiv

Takuya Miyano, Alan D. Irvine, Reiko Tanaka (2021). A mathematical model to identify optimal combinations of drug targets for dupilumab poor responders in atopic dermatitis. Allergy.

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Jesper Grønlund Holm, Guillem Hurault, Tove Agner, Maja Lisa Clausen, Sanja Kezic, Reiko Tanaka, Simon Francis Thomsen (2021). Immunoinflammatory Biomarkers in Serum Are Associated with Disease Severity in Atopic Dermatitis. Dermatology.

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Ruzica Jurakic Toncic, Ivone Jakasa, Yuxin Sun, Guillem Hurault, Suzana Ljubojevic Hadzavdic, Reiko Tanaka, Sanja Kezic, Branka Marinovic (2021). Stratum corneum markers of innate and T helper cell-related immunity and their relation to the disease severity in Croatian patients with atopic dermatitis. Journal of the European Academy of Dermatology & Venereology.

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Takuya Miyano, Reiko Tanaka (2020). Identification of keratinocyte subpopulations in transcriptome to evaluate drug effects in atopic dermatitis. British Journal of Dermatology.

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Kevin Pan, Guillem Hurault, Kailash Arulkumaran, Hywel C. Williams, Reiko Tanaka (2020). EczemaNet: Automating Detection and Severity Assessment of Atopic Dermatitis. MLMI: International Workshop on Machine Learning in Medical Imaging.

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Janna Nousbeck, Maeve A. McAleer, Guillem Hurault, E. Kenny, K. Harte, Sanja Kezic, Reiko Tanaka, Alan D. Irvine (2020). miRNA analysis of Childhood Atopic Dermatitis reveals a role for miR-451a. British Journal of Dermatology.

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Guillem Hurault, Elisa Domínguez-Hüttinger, Sinead M. Langan, Hywel C. Williams, Reiko Tanaka (2020). Personalised prediction of daily eczema severity scores using a mechanistic machine learning model. Clinical & Experimental Allergy.

Cite Code DOI MedRxiv

Maeve A. McAleer, Ivone Jakasa, Guillem Hurault, Peter Sarvari, W.H.I. McLean, Reiko Tanaka, Sanja Kezic, Alan D. Irvine (2019). Systemic and stratum corneum biomarkers of severity in infant AD include markers of innate and Th-related immunity and angiogenesis. British Journal of Dermatology.

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Kilian Eyerich, Sara J. Brown, Bethany E. Perez White, Reiko Tanaka, Robert Bissonette, Sandipan Dhar, Thomas Bieber, DirkJan Hijnen, Emma Guttman-Yassky, Alan D. Irvine, Jacob P. Thyssen, Christian Vestergaard, Thomas Werfel, Andreas Wollenberg, Amy S. Paller, Nick J. Reynolds (2019). Human and computational models of atopic dermatitis: A review and perspectives by an expert panel of the International Eczema Council. Journal of Allergy and Clinical Immunology.

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Guillem Hurault, M.E. Schram, E. Roekevisch, P.I. Spuls, Reiko Tanaka (2018). Relationship and probabilistic stratification of EASI and oSCORAD severity scores for atopic dermatitis. British Journal of Dermatology.

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Anastasia G. Giannari, Mark D.A. Van Logtestijn, Panayiotis Christodoulides, Katsumi Konishi, Reiko Tanaka (2018). Model Predictive Control for Designing Proactive Therapy of Atopic Dermatitis. 2018 European Control Conference (ECC).

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Gouhei Tanaka, Elisa Domínguez-Hüttinger, Panayiotis Christodoulides, Kazuyuki Aihara, Reiko Tanaka (2018). Bifurcation analysis of a mathematical model of atopic dermatitis to determine patient-specific effects of treatments on dynamic phenotypes. Journal of Theoretical Biology.

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Yuki Yamakawa, Kiyohiro Ikeda, Isao Saiki, Jacques Desrues, Reiko Tanaka (2017). Diffuse bifurcations engraving diverse shear bands in granular materials. International Journal for Numerical and Analytical Methods in Geomechanics.

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Elisa Domínguez-Hüttinger, Panayiotis Christodoulides, Kosuke Miyauchi, Alan D. Irvine, Mariko Okada-Hatakeyama, Masato Kubo, Reiko Tanaka (2017). Mathematical modeling of atopic dermatitis reveals “double-switch” mechanisms underlying 4 common disease phenotypes. Journal of Allergy and Clinical Immunology.

Cite DOI Media coverage: article in Imperial News Media coverage: Latest Research Summaries for American Academy of Allergy Asthma and Immunology

Alejandro A Granados, Matthew M Crane, Luis F Montano-Gutierrez, Reiko Tanaka, Margaritis Voliotis, Peter S Swain (2017). Distributing tasks via multiple input pathways increases cellular survival in stress. eLife.

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Elisa Domínguez-Hüttinger, Neville J. Boon, Thomas B. Clarke, Reiko Tanaka (2017). Mathematical modeling of $\mathit{Streptococcus}$ $\mathit{pneumoniae}$ colonization, invasive infection and treatment. Frontiers in Physiology.

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Panayiotis Christodoulides, Yoshito Hirata, Elisa Domínguez-Hüttinger, Simon G. Danby, Michael J. Cork, Hywel C. Williams, Kazuyuki Aihara, Reiko Tanaka (2017). Computational design of treatment strategies for proactive therapy on atopic dermatitis using optimal control theory. Philosophical transactions. Series A, Mathematical, physical, and engineering sciences.

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Mariko Yokouchi, Toru Atsugi, Mark van Logtestijn, Reiko Tanaka, Mayumi Kajimura, Makoto Suematsu, Mikio Furuse, Masayuki Amagai, Akiharu Kubo (2016). Epidermal cell turnover across tight junctions based on Kelvin's tetrakaidecahedron cell shape. eLife.

Cite DOI Media Coverage: Article in Imperial News Media Coverage: Why Skin Doesn't Leak

Sang Y. Lee, Neville J. Boon, Alex A.R. Webb, Reiko Tanaka (2016). Synergistic activation of RD29A via integration of salinity stress and abscisic acid in arabidopsis thaliana. Plant and Cell Physiology.

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Mark D.A. Van Logtestijn, Peter J. Caspers, Sanja Kezic, Douglas R. Hoffman, David W. Koenig, Masahiro Ono, Georgios N. Stamatas, Reiko Tanaka (2016). Water resistance profile as a marker of skin barrier damage in atopic dermatitis patients. Journal of Dermatological Science.

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Masahiro Ono, Reiko Tanaka (2016). Controversies concerning thymus-derived regulatory T cells: Fundamental issues and a new perspective. Immunology and Cell Biology.

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Reiko Tanaka, Neville J. Boon, Katarina Vrcelj, Anita Nguyen, Carmelina Vinci, Darius Armstrong-James, Elaine Bignell (2015). In silico modeling of spore inhalation reveals fungal persistence following low dose exposure. Scientific Reports.

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Mark D.A. Van Logtestijn, Elisa Domínguez-Hüttinger, Georgios N. Stamatas, Reiko Tanaka (2015). Resistance to water diffusion in the stratum corneum is depth-dependent. PLoS ONE.

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Masahiro Ono, Reiko Tanaka, Manabu Kano (2014). Visualisation of the T cell differentiation programme by Canonical Correspondence Analysis of transcriptomes. BMC Genomics.

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Quentin Sabatier, Holger G. Krapp, Reiko Tanaka (2014). Dynamic optimisation for fly gaze stabilisation based on noisy and delayed sensor information. 2014 European Control Conference.

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Reiko Tanaka, Masahiro Ono (2013). Skin disease modeling from a mathematical perspective. Journal of Investigative Dermatology.

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Elisa Domínguez-Hüttinger, Masahiro Ono, Mauricio Barahona, Reiko Tanaka (2013). Risk factor-dependent dynamics of atopic dermatitis: Modelling multi-scale regulation of epithelium homeostasis. Interface Focus.

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Naveed Ejaz, Holger G. Krapp, Reiko Tanaka (2013). Closed-loop response properties of a visual interneuron involved in fly optomotor control. Frontiers in Neural Circuits.

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Masahiro Ono, Reiko Tanaka, Manabu Kano, Toshio Sugiman (2013). Visualising the Cross-Level Relationships between Pathological and Physiological Processes and Gene Expression: Analyses of Haematological Diseases. PLoS ONE.

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David Schley, Reiko Tanaka, Kritsada Leungchavaphongse, Vahid Shahrezaei, John Ward, Clare Grant, Bryan Charleston, Christopher J. Rhodes (2012). Modelling the influence of foot-and-mouth disease vaccine antigen stability and dose on the bovine immune response. PLoS ONE.

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Naveed Ejaz, Reiko Tanaka, Holger G. Krapp (2012). Static versus adaptive gain control strategy for visuo-motor stabilization. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).

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Naveed Ejaz, Reiko Tanaka, Holger G. Krapp (2011). Closed-loop performance of a proportional controller for visual stabilization using a fly-robot interface. 2011 IEEE International Conference on Robotics and Biomimetics.

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Reiko Tanaka, Masahiro Ono, Heather A. Harrington (2011). Skin barrier Homeostasis in atopic dermatitis: Feedback regulation of kallikrein activity. PLoS ONE.

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Daniel A. Schwyn, Francisco J.H. Heras, Gino Bolliger, Matthew M. Parsons, Holger G. Krapp, Reiko Tanaka (2011). Interplay between feedback and feedforward control in fly gaze stabilization. IFAC Proceedings Volumes.

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Reiko Tanaka, Lu Gaohua, Shingo Shimoda, Hidenori Kimura (2009). Compound control - adaptation to multiple environmental changes. Proceedings of the 48h IEEE Conference on Decision and Control (CDC) held jointly with 2009 28th Chinese Control Conference, pages 6183-6188.

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Reiko Tanaka, Hidenori Kimura (2008). Mathematical classification of regulatory logics for compound environmental changes. Journal of Theoretical Biology.

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Hidenori Kimura, Hiroyuki Okano, Reiko Tanaka (2007). Stochastic approach to molecular interactions and computational theory of metabolic and genetic regulations. Journal of Theoretical Biology.

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Reiko Tanaka, Hiroyuki Okano, Hidenori Kimura (2006). Mathematical Description of Gene Regulatory Units. Biophysical Journal.

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Reiko Tanaka, M. Ceste, John C. Doyle (2005). Highly optimised global organisation of metabolic networks. IEE Proceedings - Systems Biology.

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John C. Doyle, David L. Alderson, Lun Li, Steven Low, Matthew Roughan, Stanislav Shalunov, Reiko Tanaka, Walter Willinger (2005). The “robust yet fragile” nature of the Internet. Proceedings of the National Academy of Sciences.

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Reiko Tanaka, Tau-Mu Yi, John C. Doyle (2005). Some protein interaction data do not exhibit power law statistics. FEBS Letters.

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Reiko Tanaka (2005). Scale-Rich Metabolic Networks. Physical Review Letters.

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